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XIAP Monoclonal antibody, PBS Only
XIAP Monoclonal Antibody for WB, IHC, IF-P, FC (Intra), Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat
Applications
WB, IHC, IF-P, FC (Intra), Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2A1A12
Cat no : 66800-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66800-1-PBS targets XIAP in WB, IHC, IF-P, FC (Intra), Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | XIAP fusion protein Ag18088 相同性解析による交差性が予測される生物種 |
Full Name | X-linked inhibitor of apoptosis |
Calculated molecular weight | 60 kDa |
Observed molecular weight | 57 kDa |
GenBank accession number | BC032729 |
Gene symbol | XIAP |
Gene ID (NCBI) | 331 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
XIAP, also named as API3, BIRC4 and IAP3, belongs to the IAP family. It has E3 ubiquitin-protein ligase activity. It mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells.