Validation Data Gallery
Tested Applications
Positive WB detected in | HL-60 cells, K-562 cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:2000-1:10000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
84902-1-RR targets XPR1 in WB, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | XPR1 fusion protein Ag5373 相同性解析による交差性が予測される生物種 |
Full Name | xenotropic and polytropic retrovirus receptor |
Calculated molecular weight | 696 aa, 82 kDa |
Observed molecular weight | 74 kDa |
GenBank accession number | BC041142 |
Gene Symbol | XPR1 |
Gene ID (NCBI) | 9213 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q9UBH6 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
XPR1 is a receptor for xenotropic and polytropic murine leukemia retroviruses and a homolog of yeast Syg1 and plant Pi transporter PHO1 (PMID: 20633538). XPR1 has been identified as an atypical G-protein-coupled receptor. Xenotropic or polytropic retrovirus binding to XPR1 can disrupt the cAMP-mediated signaling function of Xpr1, leading to the apoptosis of infected cells (PMID: 22090134). A band of about 82-100 kDa is probably due to abnormal migration of the protein or post-translation modifications. In addition, a band of about 55-72 kDa may be isoforms and fragments.
Protocols
Product Specific Protocols | |
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WB protocol for XPR1 antibody 84902-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |