ZMAT3 Polyclonal antibody

ZMAT3 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, IP, ELISA

Conjugate

Unconjugated

Cat no : 10504-1-AP

Synonyms

p53 activated gene 608 protein, PAG608, WIG 1, WIG1, Zinc finger protein WIG 1, zinc finger, matrin type 3, ZMAT3


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Tested Applications

Positive WB detected inCOLO 320 cells, rat testis tissue, HEK-293 cells, HepG2 cells, mouse testis tissue
Positive IP detected inmouse testis tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:16000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10504-1-AP targets ZMAT3 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ZMAT3 fusion protein Ag0780 相同性解析による交差性が予測される生物種
Full Name zinc finger, matrin type 3
Calculated molecular weight 32 kDa
Observed molecular weight 32 kDa
GenBank accession numberBC002896
Gene symbol ZMAT3
Gene ID (NCBI) 64393
RRIDAB_2217579
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ZMAT3 is a p53-induced zinc finger protein, and a role in the TP53-dependent growth regulatory pathway, contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. Acts as a bona fide target gene of p53/TP53.

Protocols

Product Specific Protocols
WB protocol for ZMAT3 antibody 10504-1-APDownload protocol
IP protocol for ZMAT3 antibody 10504-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouse

Mol Cell

Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.

Authors - Kathryn T Bieging-Rolett
humanWB

J Cell Mol Med

Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.

Authors - Jian Zhang
humanWB,IF,IP

FEBS Lett

The p53 target protein Wig-1 binds hnRNP A2/B1 and RNA Helicase A via RNA.

Authors - Prahl Magdalena M
ratWB

J Physiol Sci

Tolfenamic acid inhibits ROS-generating oxidase Nox1-regulated p53 activity in intrastriatal injection of malonic acid rats.

Authors - Xin Yang
humanIHC

Int J Gen Med

Upregulation of ZMAT3 is Associated with the Poor Prognosis of Breast Cancer

Authors - Meng Wu
humanWB

Cell Death Dis

MicroRNA-184 promotes apoptosis of trophoblast cells via targeting WIG1 and induces early spontaneous abortion.

Authors - Yuan Zhang