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m6A Monoclonal antibody, PBS Only

m6A Monoclonal Antibody for IHC, RIP, Dot Blot, ELISA, Indirect ELISA
Cat No. 68055-1-PBS
Clone No.1D5E10

Host / Isotype

Mouse / IgG3

Reactivity

chemical compound, m6a

Applications

IHC, RIP, Dot Blot, ELISA, Indirect ELISA

N6-methyladenosine, 6-N-Methyladenoside

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68055-1-PBS targets m6A in IHC, RIP, Dot Blot, ELISA, Indirect ELISA applications and shows reactivity with chemical compound, m6a samples.

Tested Reactivity chemical compound, m6a
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Immunogen Compound 相同性解析による交差性が予測される生物種
Full Name m6A
GenBank accession numberm6A
Gene Symbol
Gene ID (NCBI)
RRIDAB_2918796
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

m6A (N6-methyladenosine) is the most abundant internal modification in mammalian mRNA. This modification is installed by the m6A methyltransferases or termed "writers"such as METTL3 and METTL14, and can be reversed by demethylases that serve as "erasers" such as FTO and ALKBH5. The stability of m6A-modified mRNA is regulated by m6A reader protein YTHDFs, which recognizes m6A and reduces the stability of target transcripts. m6A modification and its regulatory proteins play critical roles in cancer pathogenesis and progression. m6A modification is also invovled in viruses life cycles, suggesting that drugs targets to m6A pathway could be used for antiviral thereapy.

Protocol for Dot Blot:
https://www.ptglab.com/protocol/68055-1-IgDotBlot.pdf

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