p57Kip2 Monoclonal antibody, PBS Only
p57Kip2 Monoclonal Antibody for WB, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat
Applications
WB, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1A12H3
Cat no : 66794-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66794-1-PBS targets p57Kip2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | p57Kip2 fusion protein Ag19927 相同性解析による交差性が予測される生物種 |
Full Name | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
Calculated molecular weight | 316 aa, 32 kDa |
Observed molecular weight | 57 kDa |
GenBank accession number | BC067842 |
Gene symbol | p57 Kip2/CDKN1C |
Gene ID (NCBI) | 1028 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life.