- HEK293 expressed
- Endotoxin-free
- Animal-component free
HumanKine® recombinant human pro IGF-II protein
Cat no : HZ-1161
Synonyms
C11orf43, FLJ22066, FLJ44734, IGF II, IGF2, INSIGF, Insulin like growth factor II, pp9974, Somatomedin A
Validation Data Gallery
Technical Specifications
GeneID | 3481 |
Species | Human |
Expression | HEK293 |
Activity | 12-80 ng/mL |
Purity | >95% |
Endotoxin | <1 EU/μg |
Accession Number | P01344 |
Molecular Mass | 25 kDa reduced and non-reduced, monomer, glycosylated |
Formulation | 10 mM Tris-HCl pH 7.4 + 350 mM NaCl, See Certificate of Analysis for details |
Species Reactivity | human,mouse |
Stability and Reconstitution
Stability and Storage | Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix. |
Background
IGF2 is a hormone involved in the regulation of cell proliferation, growth, migration, differentiation, and survival. IGF2 is mostly expressed in early embryonic and fetal development. Adult IGF2 expression occurs in the liver and epithelial cells lining the surface of the brain. IGF2 can also be detected in plasma (PMID: 24593700; 23257688)
Synonyms
C11orf43, FLJ22066, FLJ44734, IGF II, IGF2, INSIGF, Insulin like growth factor II, pp9974, Somatomedin A
Publications
Species | Title |
---|---|
Stem Cells Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration. | |
J Clin Endocrinol Metab Paracrine Pathways in Uterine Leiomyoma Stem Cells Involve Insulinlike Growth Factor 2 and Insulin Receptor A. |