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ubiquitin Recombinant antibody, PBS Only

ubiquitin Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 80992-1-PBS
Clone No.6H6

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat, hamster, yeast, dog, spinach

Applications

WB, IHC, IF/ICC, Indirect ELISA

ubiquitin B, UBB, Polyubiquitin-B, Polyubiquitin B, 6H6

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

80992-1-PBS targets ubiquitin in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, hamster, yeast, dog, spinach samples.

Tested Reactivity human, mouse, rat, hamster, yeast, dog, spinach
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ubiquitin fusion protein Ag0260 相同性解析による交差性が予測される生物種
Full Name ubiquitin B
GenBank accession numberBC000379
Gene Symbol ubiquitin
Gene ID (NCBI) 7314
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP0CG47
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Ubiquitin B (UBB) is a member of ubiquitin family, one of the most conserved proteins known. Ubiquitin B is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin B is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression.When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. Interestingly ubiquitin also becomes covalently bonded to many types of pathological inclusions which appear to be resistant to normal degradation.

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