COXIV Monoclonal antibody, PBS Only (Capture)
COXIV Monoclonal Antibody for Cytometric bead array, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
Cytometric bead array, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3C7D2
Cat no : 60251-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
60251-1-PBS targets COXIV as part of a matched antibody pair:
MP50551-2: 60251-1-PBS capture and 60251-3-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | COXIV fusion protein Ag20551 相同性解析による交差性が予測される生物種 |
Full Name | cytochrome c oxidase subunit IV isoform 1 |
Calculated molecular weight | 19.6 kDa |
Observed molecular weight | 17-18 kDa |
GenBank accession number | BC021236 |
Gene symbol | COX IV |
Gene ID (NCBI) | 1327 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
COX4I1, also named as COX4 and COXIV-1, belongs to the cytochrome c oxidase IV family. It is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. COX4I1 is a marker for mitochondria. It has two isoforms (isoform 1 and 2). Isoform 1(COX4I1) is ubiquitously expressed and isoform 2 is highly expressed in lung tissues. COX4I1 is commonly used as a loading control. This antibody is specific to COX4I1 and do not cross reacts with COX4I2.