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Recombinant Mouse CD64 protein (rFc Tag)

Species

Mouse

Purity

>90 %, SDS-PAGE

Tag

rFc Tag

Activity

not tested

Cat no : Eg2107

Validation Data Gallery

  • Purity of Recombinant Mouse CD64 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CD64 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

Product Information

Purity >90 %, SDS-PAGE
Endotoxin <0.1 EU/μg protein, LAL method
Activity 
Not tested
Expression HEK293-derived Mouse CD64 protein Glu25-Pro297 (Accession# P26151) with a rabbit IgG Fc tag at the C-terminus.
GeneID 14129
Accession P26151
PredictedSize 56.7 kDa
SDS-PAGE 60-80 kDa, reducing (R) conditions
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
Reconstitution Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
Storage Conditions
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

Fcγ receptor comprises a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG). CD64, also known as FcγRIA, is a high-affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells. CD64 functions in both innate and adaptive immune responses.

References:

1. W W Shanaka I Rodrigo, et al. (2006). J Virol. Oct;80(20):10128-38.
2. David A Mancardi, et al. (2013). Blood. Feb 28;121(9):1563-73.
3. Johannes J M L Hoffmann, et al. (2009). Clin Chem Lab Med. 47(8):903-16.
4. J M Kerst, et al. (1993). Blood. Mar 15;81(6):1457-64.