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Tested Applications
| Positive IF/ICC detected in | HeLa cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL594-60153 targets ABCD1 in IF/ICC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | ABCD1 fusion protein Ag12757 相同性解析による交差性が予測される生物種 |
| Full Name | ATP-binding cassette, sub-family D (ALD), member 1 |
| Calculated molecular weight | 745 aa, 83 kDa |
| Observed molecular weight | 75 kDa |
| GenBank accession number | BC025358 |
| Gene Symbol | ABCD1 |
| Gene ID (NCBI) | 215 |
| RRID | AB_2919897 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P33897 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 ABCD1 antibody CL594-60153 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |