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Species Reactivity

Species Reactivity

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  • Featured Product
  • KD/KO Validated

ACVR1B Polyclonal antibody, PBS Only

ACVR1B Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10086-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of HEK-293 cells using ACVR1B Polyclonal antibody (10086-1-AP)

    WB analysis of HEK-293 using 10086-1-AP (same clone as 10086-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 10086-1-AP (ACVR1B Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10086-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HepG2 cells using ACVR1B Polyclonal antibody (10086-1-AP)

    WB analysis of HepG2 using 10086-1-AP (same clone as 10086-1-PBS)

    DMSO treated HepG2 cells were subjected to SDS PAGE followed by western blot with 10086-1-AP (ACVR1B Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10086-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

10086-1-PBS targets ACVR1B in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ACVR1B fusion protein Ag0129 相同性解析による交差性が予測される生物種
Full Name activin A receptor, type IB
Calculated molecular weight 57 kDa
Observed molecular weight50 kDa
GenBank accession numberBC000254
Gene symbol ACVR1B
Gene ID (NCBI) 91
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ACVR1B (ALK4, activin A receptor type 1B) is a transforming growth factor-beta (TGF-beta) superfamily member (PMID: 37020544). A potential role for ACVR1B in regulating muscle mass is that it is part of the transforming growth factor b (TGFb) pathway regulating myostatin (PMID: 21063444).