AEG-1/MTDH Monoclonal antibody
AEG-1/MTDH Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
1D8C2
Cat no : 68592-1-Ig
Synonyms
Validation Data Gallery
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Tested Applications
| Positive WB detected in | A431 cells, MCF-10A cells, A549 cells, LNCaP cells, HeLa cells, Jurkat cells, MOLT-4 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
68592-1-Ig targets AEG-1/MTDH in WB, ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | AEG-1/MTDH fusion protein Ag5033 相同性解析による交差性が予測される生物種 |
| Full Name | metadherin |
| Calculated molecular weight | 582 aa, 64 kDa |
| Observed molecular weight | 70-80 kDa |
| GenBank accession number | BC045642 |
| Gene symbol | AEG1/MTDH |
| Gene ID (NCBI) | 92140 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22 , the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma , and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for AEG-1/MTDH antibody 68592-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
