ARL8A/ARL8B Monoclonal antibody
ARL8A/ARL8B Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, mouse, rat, rabbit
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
2F4C3
Cat no : 68186-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | rabbit brain tissue, LNCaP cells, human placenta tissue, HeLa cells, rat brain tissue, mouse brain tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:5000-1:50000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
68186-1-Ig targets ARL8A/ARL8B in WB, ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.
Tested Reactivity | Human, mouse, rat, rabbit |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | ARL8A/ARL8B fusion protein Ag10758 相同性解析による交差性が予測される生物種 |
Full Name | ADP-ribosylation factor-like 8A |
Calculated molecular weight | 186 aa, 21 kDa |
Observed molecular weight | 18 kDa, 21 kDa |
GenBank accession number | BC015408 |
Gene symbol | ARL8A |
Gene ID (NCBI) | 127829 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
ARL8A (ADP-ribosylation factor-like protein 8A) is also named as ARL10B, GIE2 and belongs to the small GTPase superfamily. ARL8A is localized to lysosomes in mammalian cells (PMID: 16537643). In neurons, ARL8A mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles that are required for presynaptic biogenesis and synaptic function. ARL8A is upregulated in many cancers such as endometrial cancer (PMID: 32070877), colorectal cancer (PMID: 30546056) and inflammatory breast cancer (PMID: 27648361), and has been associated with poor survival outcomes. ARL8A/ARL8B can be recognized by this antibody.
Protocols
Product Specific Protocols | |
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WB protocol for ARL8A/ARL8B antibody 68186-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |