ARL8A/ARL8B Monoclonal antibody, PBS Only
ARL8A/ARL8B Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, mouse, rat, rabbit
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2F4C3
Cat no : 68186-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
68186-1-PBS targets ARL8A/ARL8B in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, rabbit samples.
Tested Reactivity | Human, mouse, rat, rabbit |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | ARL8A/ARL8B fusion protein Ag10758 相同性解析による交差性が予測される生物種 |
Full Name | ADP-ribosylation factor-like 8A |
Calculated molecular weight | 186 aa, 21 kDa |
Observed molecular weight | 18 kDa, 21 kDa |
GenBank accession number | BC015408 |
Gene symbol | ARL8A |
Gene ID (NCBI) | 127829 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
ARL8A (ADP-ribosylation factor-like protein 8A) is also named as ARL10B, GIE2 and belongs to the small GTPase superfamily. ARL8A is localized to lysosomes in mammalian cells (PMID: 16537643). In neurons, ARL8A mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles that are required for presynaptic biogenesis and synaptic function. ARL8A is upregulated in many cancers such as endometrial cancer (PMID: 32070877), colorectal cancer (PMID: 30546056) and inflammatory breast cancer (PMID: 27648361), and has been associated with poor survival outcomes. ARL8A/ARL8B can be recognized by this antibody.