ASAH1 Monoclonal antibody, PBS Only
ASAH1 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, Pig, Rat, Rabbit
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2B3C7
Cat no : 67092-2-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
67092-2-PBS targets ASAH1 in WB, Indirect ELISA applications and shows reactivity with Human, Pig, Rat, Rabbit samples.
| Tested Reactivity | Human, Pig, Rat, Rabbit |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | ASAH1 fusion protein Ag28645 相同性解析による交差性が予測される生物種 |
| Full Name | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| Calculated molecular weight | 44 kDa |
| Observed molecular weight | 44-55 kDa |
| GenBank accession number | BC016828 |
| Gene symbol | ASAH1 |
| Gene ID (NCBI) | 427 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
ASAH1, also named as AC, ACDase, Acid CDase, PHP32 and ASAH, belongs to the acid ceramidase family. ASAH1 is a lipid hydrolase that catalyzes the conversion of ceramide (cer) into sphingosine (SPH) and a free fatty acid. Mutation of ASAH1 will cause the Farber lipogranulomatosis (FL) which also known as Farber disease (FD). ASAH1 is highly expressed in Heart. And it is first synthesized as an 55-60 kDa precursor and subsequently processed to the mature, heterodimeric enzyme (40 + 13 kDa) in the endosomes/lysosomes.
