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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

BMPR2 Monoclonal antibody, PBS Only

BMPR2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C1D7

Cat no : 68497-1-PBS

Synonyms

BMP type 2 receptor, BMP type II receptor, BMPR 2, BMPR II, BMPR2, BMPR3, BMR2, BRK 3, FLJ41585, FLJ76945, PPH1, T ALK

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using BMPR2 Monoclonal antibody (68497-1-Ig)

    WB analysis using 68497-1-Ig (same clone as 68497-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68497-1-Ig (BMPR2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68497-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NIH/3T3 cells using BMPR2 Monoclonal antibody (68497-1-Ig)

    WB analysis of NIH/3T3 using 68497-1-Ig (same clone as 68497-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 68497-1-Ig (BMPR2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68497-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68497-1-PBS targets BMPR2 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.

Tested Reactivity Human, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen BMPR2 fusion protein Ag5868 相同性解析による交差性が予測される生物種
Full Name bone morphogenetic protein receptor, type II (serine/threonine kinase)
Calculated molecular weight 115 kDa
Observed molecular weight120-140 kDa
GenBank accession numberBC052985
Gene symbol BMPR2
Gene ID (NCBI) 659
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

BMPs (bone morphogenetic protein) are involved in endochondral bone formation and embryogenesis. BMPR2 encodes a member of the (BMP) receptor family of transmembrane serine/threonine kinases. It is a widely expressed receptor, with high mRNA expression during development in many tissues. The dimer of BMPR2 receptors (70-80 kD) forms a complex with a dimer of type I BMPR1(50-55 kD) in signal transduction. This antibody recognizes endogenous levels of total BMPR2 protein, including 115 kD precursor, 75 kD mature form, and 150 kD dimer.