Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
28241-1-PBS targets BZRAP1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | BZRAP1 fusion protein Ag28198 相同性解析による交差性が予測される生物種 |
| Full Name | benzodiazapine receptor (peripheral) associated protein 1 |
| Calculated molecular weight | 1857 aa, 200 kDa |
| Observed molecular weight | 200-235 kDa |
| GenBank accession number | BC146852 |
| Gene Symbol | BZRAP1 |
| Gene ID (NCBI) | 9256 |
| RRID | AB_2881096 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95153 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
BZRAP1, also named as TSPOAP1 and PBR-associated protein 1 (PRAX-1), is a cytoplasmic protein of 1857 residues. It plays a key role in inflammation, neuroinflammation, mental and metabolic diseases, and cancer. BZRAP1 predominantly expressed in the central nervous system, pituitary gland, and thymus, specially abundant in the CA1 subfield of the hippocampus. Tumor necrosis factor receptor 1 (TNFR1), vascular cell adhesion molecule 1 (VCAM1), cyclic AMP response element-binding protein 1 (CREB1), T-cell receptor (TCR), nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NLRP3), DNA-dependent protein kinase (DNA-PK or PRKDC), and mitochondrial permeability transition pore (mPTP) were the major interaction partners of BZRAP1 (PMID: 34212002).