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  • Featured Product
  • KD/KO Validated

Beta Arrestin 1 Monoclonal antibody, PBS Only

Beta Arrestin 1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H8E4

Cat no : 67580-1-PBS

Synonyms

ARB1, ARR1, ARRB1, Arrestin beta 1, arrestin, beta 1, Beta arrestin 1

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using Beta Arrestin 1 Monoclonal antibody (67580-1-Ig)

    WB analysis using 67580-1-Ig (same clone as 67580-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HepG2 cells using Beta Arrestin 1 Monoclonal antibody (67580-1-Ig)

    WB analysis of HepG2 using 67580-1-Ig (same clone as 67580-1-PBS)

    WB result of Beta Arrestin 1 antibody (67580-1-Ig; 1:8000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Beta Arrestin 1 transfected HepG2 cells. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using Beta Arrestin 1 Monoclonal antibody (67580-1-Ig)

    WB analysis of HeLa using 67580-1-Ig (same clone as 67580-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NIH/3T3 cells using Beta Arrestin 1 Monoclonal antibody (67580-1-Ig)

    WB analysis of NIH/3T3 using 67580-1-Ig (same clone as 67580-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human peripheral blood platelets using Beta Arrestin 1 Monoclonal antibody (67580-1-Ig)

    WB analysis of human peripheral blood platelets using 67580-1-Ig (same clone as 67580-1-PBS)

    Human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67580-1-PBS targets Beta Arrestin 1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen Beta Arrestin 1 fusion protein Ag7504 相同性解析による交差性が予測される生物種
Full Name arrestin, beta 1
Calculated molecular weight 47 kDa
Observed molecular weight 45-55 kDa
GenBank accession numberBC003636
Gene symbol Beta Arrestin 1
Gene ID (NCBI) 408
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

β-Arrestins (ARRBs), the best known regulators of G protein-coupled receptor signaling, are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including cell growth, apoptosis and immune responses. Overexpression of beta Arrestin 1 has been found in various cancers, indicating it as a potential therapeutic target for cancer treatment. Recently expression of ARRB1 in saliva has been identified as a candidate circadian biomarker. ARRB1 migrated as a doublet of two bands of 45 and 55 kDa (PMID:28947386).