Validation Data Gallery
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Tested Applications
| Positive WB detected in | U-937 cells, mouse thymus tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
82942-1-RR targets CCR5 in WB, ELISA applications and shows reactivity with Human, mouse samples.
| Tested Reactivity | Human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CCR5 fusion protein Ag11493 相同性解析による交差性が予測される生物種 |
| Full Name | chemokine (C-C motif) receptor 5 |
| Calculated molecular weight | 352 aa, 41 kDa |
| Observed molecular weight | 45 kDa |
| GenBank accession number | BC038398 |
| Gene Symbol | CCR5 |
| Gene ID (NCBI) | 1234 |
| RRID | AB_3670685 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P51681 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
CCR5 (also known as CD195) is a member of the beta chemokine receptor family. This protein is expressed by T cells and macrophages and is known to be an important co-receptor for macrophage-tropic viruses, including HIV, to enter host cells. The natural chemokine ligands that bind to CCR5 include MIP-1-alpha, MIP-1-beta, MCP-2, and RANTES.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for CCR5 antibody 82942-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |