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PE-Cyanine7-conjugated CD11b Monoclonal antibody

CD11b Monoclonal Antibody for FC
Cat No. PE-Cyanine7-65055
Clone No.M1/70

Host / Isotype

Rat / IgG2b, kappa

Reactivity

Mouse, Human

Applications

Cd11b, CD11b/CD18, CR3, CR3A, F730045J24Rik, integrin alpha M, Itgam, Ly 40, Mac 1, Mac 1a, MAC1

Formulation:  PBS and Azide
PBS and Azide
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

PE-Cyanine7-65055 targets CD11b in applications and shows reactivity with Mouse, Human samples.

Tested Reactivity Mouse, Human
Host / Isotype Rat / IgG2b, kappa
Class Monoclonal
Type Antibody
Immunogen C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes 相同性解析による交差性が予測される生物種
Full Name integrin alpha M
Calculated molecular weight127 kDa
GenBank accession numberBC156991
Gene Symbol CD11b
Gene ID (NCBI) 16409
Conjugate PE-Cyanine7 Fluorescent Dye
Excitation/Emission maxima wavelengths450-500 nm / 778 nm
Form Liquid
Purification MethodAffinity purification
UNIPROT IDE9Q604
Storage Buffer PBS with 0.09% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

Protocols

Product Specific Protocols
FC protocol for PE-Cyanine7 CD11b antibody PE-Cyanine7-65055Download protocol
Standard Protocols
Click here to view our Standard Protocols
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