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CD32A/C Polyclonal antibody, PBS Only

CD32A/C Polyclonal Antibody for WB, Indirect ELISA
Cat No. 25323-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

25323-1-PBS targets CD32A/C in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CD32A/C fusion protein Ag18123 相同性解析による交差性が予測される生物種
Full Name Fc fragment of IgG, low affinity IIc, receptor for (CD32)
Calculated molecular weight 323 aa, 36 kDa
Observed molecular weight40 kDa
GenBank accession numberBC137397
Gene Symbol CD32A/C
Gene ID (NCBI) 9103
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP31995
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

IgG Fc receptors (FcγRs) play important roles in immune responses. The low-affinity IgG Fc receptor, FcγRII (CD32), consists of a family of primarily cell membrane receptor proteins: CD32A, CD32B, and CD32C. They are encoded by the mRNA splice variants of three highly related genes: FCGR2A, FCGR2B, and FCGR2C (PMID: 30941127). CD32 is present on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. This antibody raised against 254-323 aa of human CD32C (FCGR2C) can recognize both CD32A and CD32C forms.

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