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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Anti-Human CD41a (HIP8)

CD41a Monoclonal Antibody for FC

Host / Isotype

Mouse / Mouse IgG1

Reactivity

Non-human primates, Human

Applications

FC

Conjugate

Unconjugated

CloneNo.

HIP8

Cat no : 65173-1-Ig

Synonyms

CD41, CD41a, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HIP8, HPA3, Integrin alpha IIb, ITGA2B, ITGAB

Validation Data Gallery

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  • Flow cytometry (FC) experiment of human peripheral blood platelets using Anti-Human CD41a (HIP8) (65173-1-Ig)

    FC experiment of human peripheral blood platelets using 65173-1-Ig

    1X10^6 human peripheral blood platelets were surface stained with 0.40 ug Purified Anti-Human CD41a (65173-1-Ig, Clone:HIP8) (red) or 0.40 ug Mouse IgG1 Isotype Control (blue) and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) with dilution 1:1000. Cells were not fixed.

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Tested Applications

Positive FC detected inHuman peripheral blood platelets

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

65173-1-Ig targets CD41a in FC applications and shows reactivity with Non-human primates, Human samples.

Tested Reactivity Non-human primates, Human
Host / Isotype Mouse / Mouse IgG1
Class Monoclonal
Type Antibody
Immunogen N/A 相同性解析による交差性が予測される生物種
Full Name integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
GenBank accession numberBC117443
Gene symbol CD41a
Gene ID (NCBI) 3674
RRIDAB_2881482
Conjugate Unconjugated
Form Liquid
Purification MethodPurified by protein-A affinity chromatography
Storage Buffer PBS with 0.1% sodium azide.
Storage ConditionsStore at 2-8°C.

Background Information

The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands (PMID: 17543136). They are transmembrane αβ heterodimers and at least 24 distinct integrin heterodimers are formed by the combination of 18 α and eight β known subunits (PMID: 17543136; 20029421). In addition to mediating cell adhesion, integrins also play important roles in modulating signal transduction pathways that control cellular responses including migration, proliferation, differentiation, and apoptosis (PMID:19118207). Integrin alpha-IIb (ITGA2B, CD41) is expressed on platelets, megakaryocytes and some hematopoietic progenitor cells (PMID: 11934866).

Protocols

Product Specific Protocols
FC protocol for CD41a antibody 65173-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols