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CoraLite® Plus 488-conjugated CDK5 Polyclonal antibody
CDK5 Polyclonal Antibody for IF/ICC
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IF/ICC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-10430
Synonyms
Validation Data Gallery
Tested Applications
Positive IF/ICC detected in | SH-SY5Y cells |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL488-10430 targets CDK5 in IF/ICC applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | CDK5 fusion protein Ag0686 相同性解析による交差性が予測される生物種 |
Full Name | cyclin-dependent kinase 5 |
Calculated molecular weight | 31 kDa, 33 kDa |
Observed molecular weight | 33 kDa |
GenBank accession number | BC005115 |
Gene symbol | CDK5 |
Gene ID (NCBI) | 1020 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Cyclin-dependent kinase 5 (CDK5), belongs to the cyclin-dependent kinase family, is a proline-directed serine/threonine-protein kinase that essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. CDK5 predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau.
Protocols
Product Specific Protocols | |
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IF protocol for CL Plus 488 CDK5 antibody CL488-10430 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |