CEACAM1/CD66a Recombinant antibody, PBS Only (Capture)
CEACAM1/CD66a Recombinant Antibody for WB, IHC, Cytometric bead array, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, IHC, Cytometric bead array, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
240497B4
Cat no : 83524-3-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
83524-3-PBS targets CEACAM1/CD66a as part of a matched antibody pair:
MP00520-2: 83524-3-PBS capture and 83524-4-PBS detection (validated in Cytometric bead array)
MP00520-3: 83524-3-PBS capture and 83524-2-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Fusion Protein 相同性解析による交差性が予測される生物種 |
Full Name | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Calculated molecular weight | 526 aa, 58 kDa |
Observed molecular weight | 135-150 kDa |
GenBank accession number | BC014473 |
Gene symbol | CEACAM1 |
Gene ID (NCBI) | 634 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530).