CLEC2D Polyclonal antibody, PBS Only

CLEC2D Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13188-1-PBS

Synonyms


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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

13188-1-PBS targets CLEC2D in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CLEC2D fusion protein Ag3862 相同性解析による交差性が予測される生物種
Full Name C-type lectin domain family 2, member D
Calculated molecular weight 154 aa, 18 kDa
Observed molecular weight 33 kDa
GenBank accession numberBC019883
Gene symbol CLEC2D
Gene ID (NCBI) 29121
RRIDAB_2877920
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts (PMID: 21930700; 14753741). Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs (PMID: 21930700). CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and their interaction differentially regulates NK- and T-cell functions (PMID: 16339513, 16339512). It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells (PMID:14753741; 20415786).