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Clusterin 抗体 10 文献

Rabbit Polyclonal| カタログ番号: 12289-1-AP

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Related Primary Antibodies

適用アプリケーション

アプリケーション:
WB, IHC, CoIP,ELISA
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Images See all

Clusterin Antibody WB human plasma 12289-1-AP

human plasma were subjected to SDS PAGE followed by western blot with 12289-1-AP (Clusterin antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Clusterin Antibody IHC human tonsillitis tissue 12289-1-AP

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 12289-1-AP (Clusterin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Clusterin Antibody IHC human tonsillitis tissue 12289-1-AP

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 12289-1-AP (Clusterin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

種特異性:
human, mouse, rat
WB ポジティブ:
human plasma tissue
IHC ポジティブ:
human tonsillitis tissue, human breast cancer tissue, human liver cancer tissue
推奨希釈倍率:
WB : 1:500-1:2000
IHC : 1:50-1:500

Protocols

Product-specific protocols

Standard Protocols

製品情報

由来:
Rabbit
精製方法:
Antigen affinity purification
アイソタイプ:
IgG
バッファー/保存方法:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

ターゲット情報

免疫原:
Clusterin fusion protein Ag2889
正式名:
clusterin
計算分子量:
449 aa, 53 kDa
検出分子量:
37 kDa
GenBank accession number:
BC010514
Gene ID (NCBI):
1191
遺伝子シンボル:
CLU
別名:
AAG4, Apo J, APOJ, ApoJalpha, ApoJbeta, Apolipoprotein J, CLI, CLU, clusterin, Complement cytolysis inhibitor, Ku70 binding protein 1, KUB1, NA1/NA2, SGP 2, SGP2, SP 40, TRPM 2, TRPM2

背景説明

Clusterin (Apolipoprotein J) is a 75-80 kDa heterodimeric glycoprotein produced by a wide array of tissues and found in most biologic fluids (PMID: 7648419; 11906815). It is encoded by one single gene and cleaved posttranslationally into α (34-36 kDa) and β (36-39 kDa) subunits prior to secretion from the cell. Many functions have been described for clusterin, including regulating apoptosis, transporting lipids, controlling cell interactions, regulating complement (PMID: 10694874).


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