COL17A1 Polyclonal antibody, PBS Only
COL17A1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
Cat no : 31190-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
31190-1-PBS targets COL17A1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | COL17A1 fusion protein Ag34645 相同性解析による交差性が予測される生物種 |
Full Name | collagen, type XVII, alpha 1 |
Observed molecular weight | 180 kDa |
GenBank accession number | BC168368 |
Gene symbol | COL17A1 |
Gene ID (NCBI) | 1308 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity Purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Collagen alpha-1(XVII) chain, also termed 180-kDa bullous pemphigoid antigen (BP180), is a type II transmembrane glycoprotein with a collagenous carboxyl-terminal extracellular domain and a noncollagenous amino-terminal cytoplasmic domain. High expression of COL17A1 has also been identified as a marker of human esophageal quiescent stem/progenitor cells (PMID: 35709398, 9545306). As a structural component of the hemidesmosome, COL17A1 is not only present as the full-length 180 kDa transmembrane form, but also as a cleaved 120 kDa soluble form that is further processed to a 97 kDa form (PMID: 113594550).