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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CORO1C Monoclonal antibody, PBS Only

CORO1C Monoclonal Antibody for WB, IF/ICC, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, ELISA

Conjugate

Unconjugated

CloneNo.

1B10G4

Cat no : 68846-1-PBS

Synonyms

CRN2, Coronin-3, Coronin-1C, Coronin 3, Coronin 1C

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using CORO1C Monoclonal antibody (68846-1-Ig)

    WB analysis using 68846-1-Ig (same clone as 68846-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68846-1-Ig (CORO1C antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68846-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using CORO1C Monoclonal antibody (68846-1-Ig)

    WB analysis using 68846-1-Ig (same clone as 68846-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68846-1-Ig (CORO1C antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68846-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of SH-SY5Y cells using CORO1C Monoclonal antibody (68846-1-Ig)

    IF Staining of SH-SY5Y using 68846-1-Ig (same clone as 68846-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using CORO1C antibody (68846-1-Ig, Clone: 1B10G4 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 68846-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68846-1-PBS targets CORO1C in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen CORO1C fusion protein Ag6546 相同性解析による交差性が予測される生物種
Full Name coronin, actin binding protein, 1C
Calculated molecular weight 53 kDa
Observed molecular weight 57 kDa
GenBank accession numberBC002342
Gene symbol CORO1C
Gene ID (NCBI) 23603
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CORO1C also known as HCRNN4, belongs to the WD repeat coronin family. CORO1C contains 5 N-terminal trp-asp (WD) repeats and a C-terminal coiled-coil motif. It was reported to regulate actin‐dependent processes by assembling F-actin. CORO1C promoted the invasion of breast cancer and glioma cells by specifically promoting the formation of invadopodia(PMID: 30974047).