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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated CORO1C Polyclonal antibody

CORO1C Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-14749

Synonyms

CRNN4, CRN2, Coronin-3, Coronin-1C, Coronin 3

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of SH-SY5Y cells using CoraLite® Plus 488-conjugated CORO1C Polyclonal an (CL488-14749)

    IF Staining of SH-SY5Y using CL488-14749

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using CoraLite® Plus 488 CORO1C antibody (CL488-14749) at dilution of 1:200.

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Tested Applications

Positive IF/ICC detected inSH-SY5Y cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-14749 targets CORO1C in IF/ICC applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CORO1C fusion protein Ag6488 相同性解析による交差性が予測される生物種
Full Name coronin, actin binding protein, 1C
Calculated molecular weight 53 kDa
Observed molecular weight 57 kDa
GenBank accession numberBC002342
Gene symbol CORO1C
Gene ID (NCBI) 23603
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CORO1C also known as HCRNN4, belongs to the WD repeat coronin family. CORO1C contains 5 N-terminal trp-asp (WD) repeats and a C-terminal coiled-coil motif. It was reported to regulate actin‐dependent processes by assembling F-actin. CORO1C promoted the invasion of breast cancer and glioma cells by specifically promoting the formation of invadopodia(PMID: 30974047).

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 CORO1C antibody CL488-14749Download protocol
Standard Protocols
Click here to view our Standard Protocols