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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated CP110 Polyclonal antibody

CP110 Polyclonal Antibody for IF/ICC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-12780

Synonyms

Centrosomal protein of 110 kDa, CP110, CP110 protein, DKFZp781G1416, KIAA0419

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using CoraLite® Plus 488-conjugated CP110 Polyclonal ant (CL488-12780)

    IF Staining of HeLa using CL488-12780

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using CoraLite® Plus 488 CP110 antibody (CL488-12780) at dilution of 1:100.

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Tested Applications

Positive IF/ICC detected inHeLa cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-12780 targets CP110 in IF/ICC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CP110 fusion protein Ag3489 相同性解析による交差性が予測される生物種
Full Name CP110 protein
Calculated molecular weight 991 aa, 111 kDa
Observed molecular weight 113 kDa
GenBank accession numberBC036654
Gene symbol CP110
Gene ID (NCBI) 9738
RRIDAB_2919060
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 CP110 antibody CL488-12780Download protocol
Standard Protocols
Click here to view our Standard Protocols