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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated C-Reactive Protein/CRP Monoclonal antibody

C-Reactive Protein/CRP Monoclonal Antibody for IF-P

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat, pig

Applications

IF-P

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

3F10A11

Cat no : CL488-66250

Synonyms

CRP, PTX1, C-reactive protein(1-205), C-Reactive Protein, C reactive protein

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of human liver tissue using CoraLite® Plus 488-conjugated CRP Monoclonal antib (CL488-66250)

    IF Staining of human liver using CL488-66250

    Immunofluorescent analysis of (4% PFA) fixed human liver tissue using CL488-66250 (CRP antibody) at dilution of 1:100.

  • Immunofluorescence (IF) / fluorescent staining of human liver tissue using CoraLite® Plus 488-conjugated CRP Monoclonal antib (CL488-66250)

    IF Staining of human liver using CL488-66250

    Immunofluorescent analysis of (4% PFA) fixed human liver tissue using CL488-66250 (CRP antibody) at dilution of 1:100.

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Tested Applications

Positive IF-P detected inhuman liver tissue

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-66250 targets C-Reactive Protein/CRP in IF-P applications and shows reactivity with human, mouse, rat, pig samples.

Tested Reactivity human, mouse, rat, pig
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen C-Reactive Protein/CRP fusion protein Ag9883 相同性解析による交差性が予測される生物種
Full Name C-reactive protein, pentraxin-related
Calculated molecular weight 224 aa, 25 kDa
Observed molecular weight 27 kDa
GenBank accession numberBC020766
Gene symbol CRP
Gene ID (NCBI) 1401
RRIDAB_2883294
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 C-Reactive Protein/CRP antibody CL488-66250Download protocol
Standard Protocols
Click here to view our Standard Protocols