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Anti-Human CXCL10/IP-10 Rabbit Recombinant Antibody, PBS Only

CXCL10/IP-10 Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 98265-1-PBS
Clone No.242013E12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC (Intra)

CXCL10, CXCL10/IP10, IP10, CXCL 10, C-X-C motif chemokine 10

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

98265-1-PBS targets CXCL10/IP-10 in FC (Intra) applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein 相同性解析による交差性が予測される生物種
Full Name chemokine (C-X-C motif) ligand 10
Calculated molecular weight 11 kDa
GenBank accession numberBC010954
Gene Symbol CXCL10
Gene ID (NCBI) 3627
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP02778
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CXCL10 (also known as IP-10) is a member of the CXC chemokine family which binds to the CXCR3 receptor to exert its biological effects. CXCL10 is a 12-kDa protein and constitutes two internal disulfide cross bridges. The predicted signal peptidase cleavage generates a 10-kDa secreted polypeptide with four conserved cysteine residues in the N-terminal. The CXCL10 gene localizes on chromosome 4 at band q21, a locus associated with an acute monocytic/B-lymphocyte lineage leukemia exhibiting translocation of t (4; 11) (q21; q23). CXCL10 mediates leukocyte trafficking, adaptive immunity, inflammation, haematopoiesis and angiogenesis. Under proinflammatory conditions CXCL10 is secreted from a variety of cells, such as leukocytes, activated neutrophils, eosinophils, monocytes, epithelial cells, endothelial cells, stromal cells (fibroblasts) and keratinocytes in response to IFN-γ.

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