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Anti-Human CXCL10/IP-10 Rabbit Recombinant Antibody

CXCL10/IP-10 Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 98265-1-RR
Clone No.242013E12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC (Intra)

CXCL10, CXCL10/IP10, IP10, CXCL 10, C-X-C motif chemokine 10

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration:  100 μg, 1000 μg/ml
100 μg, 1000 μg/ml

¥19,000/ 100 μg

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Tested Applications

Positive FC (Intra) detected inIFN gamma and brefeldin A treated human PBMCs

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98265-1-RR targets CXCL10/IP-10 in FC (Intra) applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein 相同性解析による交差性が予測される生物種
Full Name chemokine (C-X-C motif) ligand 10
Calculated molecular weight 11 kDa
GenBank accession numberBC010954
Gene Symbol CXCL10
Gene ID (NCBI) 3627
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP02778
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

Background Information

CXCL10 (also known as IP-10) is a member of the CXC chemokine family which binds to the CXCR3 receptor to exert its biological effects. CXCL10 is a 12-kDa protein and constitutes two internal disulfide cross bridges. The predicted signal peptidase cleavage generates a 10-kDa secreted polypeptide with four conserved cysteine residues in the N-terminal. The CXCL10 gene localizes on chromosome 4 at band q21, a locus associated with an acute monocytic/B-lymphocyte lineage leukemia exhibiting translocation of t (4; 11) (q21; q23). CXCL10 mediates leukocyte trafficking, adaptive immunity, inflammation, haematopoiesis and angiogenesis. Under proinflammatory conditions CXCL10 is secreted from a variety of cells, such as leukocytes, activated neutrophils, eosinophils, monocytes, epithelial cells, endothelial cells, stromal cells (fibroblasts) and keratinocytes in response to IFN-γ.

Protocols

Product Specific Protocols
FC protocol for CXCL10/IP-10 antibody 98265-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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