- Featured Product
- KD/KO Validated
ERAB Monoclonal antibody, PBS Only (Capture)
ERAB Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat
Applications
WB, IHC, Cytometric bead array, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1G5E5
Cat no : 60069-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
60069-1-PBS targets ERAB as part of a matched antibody pair:
MP50654-2: 60069-1-PBS capture and 60069-4-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | ERAB fusion protein Ag1020 相同性解析による交差性が予測される生物種 |
Full Name | hydroxysteroid (17-beta) dehydrogenase 10 |
Calculated molecular weight | 26 kDa |
Observed molecular weight | 27 kDa |
GenBank accession number | BC008708 |
Gene symbol | ERAB |
Gene ID (NCBI) | 3028 |
RRID | AB_2119779 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
HSD17B10 (3-hydroxyacyl-CoA dehydrogenase type-2) is a multifunctional mitochondrial enzyme that acts on a wide spectrum of substrates, including neuroactive steroids, alcohols, leucine, and fatty acids, with a preference for short-chain methyl-branched acyl-CoAs(PMID:15860413).It has 2 isoforms produced by alternative splicing.Defects in HSD17B10 are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD deficiency) and mental retardation syndromic X-linked type 10 (MRXS10).