EXOC3L2 Monoclonal antibody, PBS Only
EXOC3L2 Monoclonal Antibody for WB, IF, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
WB, IF, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3C1C2
Cat no : 66537-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66537-1-PBS targets EXOC3L2 in WB, IF, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | EXOC3L2 fusion protein Ag26912 相同性解析による交差性が予測される生物種 |
Full Name | exocyst complex component 3-like 2 |
Calculated molecular weight | 46 kDa |
Observed molecular weight | 46 kDa |
GenBank accession number | BC104947 |
Gene symbol | EXOC3L2 |
Gene ID (NCBI) | 90332 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The exocyst is a protein complex that ensures spatial targeting of exocytotic vesicles to the plasma membrane. Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells (PMID: 21566143). The gene of human EXOC3L2 maps to chromosome 19q13.32 and encodes a deduced 409-amino acid protein with a calculated molecular mass of about 46 kDa. Mouse Exoc3l2 gene encodes an approximately 250-amino acid protein that lacks the N-terminal domain of human EXOC3L2. Mutations in EXOC3L2 gene may be associated with Alzheimer's disease.