FGL2 Monoclonal antibody, PBS Only
FGL2 Monoclonal Antibody for WB, IF, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human, mouse
Applications
WB, IF, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2C9C5
Cat no : 67152-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67152-1-PBS targets FGL2 in WB, IF, Indirect ELISA applications and shows reactivity with Human, mouse samples.
Tested Reactivity | Human, mouse |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | FGL2 fusion protein Ag28619 相同性解析による交差性が予測される生物種 |
Full Name | fibrinogen-like 2 |
Calculated molecular weight | 50 kDa |
Observed molecular weight | 70 kDa |
GenBank accession number | BC017813 |
Gene symbol | FGL2 |
Gene ID (NCBI) | 10875 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites.