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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
67649-1-PBS targets GNE in WB, Indirect ELISA applications and shows reactivity with Human, rat samples.
| Tested Reactivity | Human, rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | GNE fusion protein Ag18702 相同性解析による交差性が予測される生物種 |
| Full Name | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| Calculated molecular weight | 722 aa, 79 kDa |
| Observed molecular weight | 79 kDa |
| GenBank accession number | BC121179 |
| Gene Symbol | GNE |
| Gene ID (NCBI) | 10020 |
| RRID | AB_2882849 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q9Y223 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
The bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.