GSDMD Monoclonal antibody, PBS Only
GSDMD Monoclonal Antibody for WB, IF/ICC, IP, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
WB, IF/ICC, IP, ELISA
Conjugate
Unconjugated
CloneNo.
2E6C7
Cat no : 66387-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66387-1-PBS targets GSDMD in WB, IF/ICC, IP, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | GSDMD fusion protein Ag16827 相同性解析による交差性が予測される生物種 |
Full Name | gasdermin D |
Calculated molecular weight | 484 aa, 53 kDa |
Observed molecular weight | 47-53 kDa |
GenBank accession number | BC008904 |
Gene symbol | GSDMD |
Gene ID (NCBI) | 79792 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.