IFI16 Monoclonal antibody, PBS Only
IFI16 Monoclonal Antibody for WB, IF, IHC, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
CloneNo.
1C10D7
Cat no : 67790-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67790-1-PBS targets IFI16 in WB, IF, IHC, ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | IFI16 fusion protein Ag30314 相同性解析による交差性が予測される生物種 |
Full Name | interferon, gamma-inducible protein 16 |
Calculated molecular weight | 729 aa, 82 kDa |
Observed molecular weight | 85-95 kDa |
GenBank accession number | BC017059 |
Gene symbol | IFI16 |
Gene ID (NCBI) | 3428 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. |
Background Information
IFI16 is a member of a family of interferon-inducible nuclear proteins involved in transcriptional regulation functions as a transcriptional repressor. IFI16 may be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA binding and modulating TP53 phosphorylation status. It has been reported that IFI16 participates in the regulation of autophagy, TP53-mediated cell death and innate immune response. IFI16 has different isoforms and 67790-1-Ig antibody detects proteins around 85-95 kDa in SDS-PAGE similar to papers. (PMID: 9718316, 14990579, 11146555, 22046441)