CoraLite® Plus 405 Anti-Rat IL-2 Rabbit Recombinant Antibody
IL-2 Recombinant Antibody for FC (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
rat
Applications
FC (Intra)
Conjugate
CoraLite® Plus 405 Fluorescent Dye
CloneNo.
240264C7
Cat no : CL405-98046
Synonyms
Validation Data Gallery
Tested Applications
| Positive FC (Intra) detected in | PMA and ionomycin treated rat splenocytes |
Recommended dilution
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
The immunogen of CL405-98046 is IL-2 Fusion Protein expressed in E. coli.
| Tested Reactivity | rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Fusion Protein 相同性解析による交差性が予測される生物種 |
| Full Name | interleukin 2 |
| Calculated molecular weight | 18 kDa |
| GenBank accession number | NM_053836 |
| Gene symbol | Il2 |
| Gene ID (NCBI) | 116562 |
| Conjugate | CoraLite® Plus 405 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 399 nm / 422 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.09% sodium azide. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
Interleukin-2 (IL-2) is a four-helix bundle, type I cytokine that functions as a growth factor for a wide range of leukocytes. In the immune system, IL-2 is essential for immune homeostasis, normal T regulatory cell function, and self-tolerance. It regulates immune cell homeostasis and has been used to treat a range of disorders including cancer and autoimmune disease. IL-2 signals through heterodimerization of the IL-2Rβ and IL-2Rγ receptor subunits (PMID: 25992858, 24907378, 15034008, 17981641).
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 405 IL-2 antibody CL405-98046 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
