CoraLite®594-conjugated IL-1R2 Monoclonal antibody
IL-1R2 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse
Applications
IF/ICC
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
3H4H4
Cat no : CL594-60262
Synonyms
Validation Data Gallery
Tested Applications
Positive IF/ICC detected in | HeLa cells |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
The immunogen of CL594-60262 is IL-1R2 Fusion Protein expressed in E. coli.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | IL-1R2 fusion protein Ag4495 相同性解析による交差性が予測される生物種 |
Full Name | interleukin 1 receptor, type II |
Calculated molecular weight | 398 aa, 45 kDa |
Observed molecular weight | 45 kDa |
GenBank accession number | BC039031 |
Gene symbol | IL1R2 |
Gene ID (NCBI) | 7850 |
RRID | AB_2883451 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.
Protocols
Product Specific Protocols | |
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IF protocol for CL594 IL-1R2 antibody CL594-60262 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |