IRF5 Monoclonal antibody, PBS Only
IRF5 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3A4A10
Cat no : 66835-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66835-1-PBS targets IRF5 in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.
Tested Reactivity | Human, mouse |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | IRF5 fusion protein Ag5442 相同性解析による交差性が予測される生物種 |
Full Name | interferon regulatory factor 5 |
Calculated molecular weight | 56 kDa |
Observed molecular weight | 56 kDa |
GenBank accession number | BC004201 |
Gene symbol | IRF5 |
Gene ID (NCBI) | 3663 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. It is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10). IRF5 is also used as M1 marcrophage lineage marker. Alternative splice variant encoding different isoforms exist.