Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
83812-1-PBS targets KMO in WB, IHC, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | KMO fusion protein Ag35029 相同性解析による交差性が予測される生物種 |
Full Name | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
Calculated molecular weight | 486 aa, 56 kDa |
Observed molecular weight | 52-56 kDa |
GenBank accession number | BC005297 |
Gene Symbol | KMO |
Gene ID (NCBI) | 8564 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | O15229 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
KMO(Kynurenine 3-monooxygenase) is an NADPH-dependent flavin monooxygenase, catalysing the hydroxylation of the L-kynurenine to form L-3-hydroxykynurenine. KMO is a membrane protein located on the outer membrane of mitochondria. Tissue distribution studies have revealed that, in rats, highest enzyme activity is found in kidney and liver, with brain having the least activity in comparison to peripheral organs(PMID: 9237672).