Lamin B2 Recombinant antibody
Lamin B2 Recombinant Antibody for IF, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
IF, ELISA
Conjugate
Unconjugated
CloneNo.
230184G4
Cat no : 82801-3-RR
Synonyms
Validation Data Gallery
Tested Applications
| Positive IF detected in | HepG2 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:400-1:1600 |
| Sample-dependent, check data in validation data gallery | |
Product Information
82801-3-RR targets Lamin B2 in IF, ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Lamin B2 fusion protein Ag1335 相同性解析による交差性が予測される生物種 |
| Full Name | lamin B2 |
| Calculated molecular weight | 68 kDa |
| GenBank accession number | BC006551 |
| Gene symbol | LMNB2 |
| Gene ID (NCBI) | 84823 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Lamins are nuclear membrane structural components that are important in structural integrity of the nucleus and may also interact with chromatin (PMID: 33033404). Research studies show that lamin B2 knockout mice exhibit neuronal developmental defects and that both proteins are essential for typical brain development (PMID: 20145110). Mutations in Lamin B2 can result in a susceptibility to developing acquired partial lipodystrophy, a rare disorder characterized by the progressive loss of subcutaneous fat in a bilaterally symmetrical fashion (PMID: 16826530).
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for Lamin B2 antibody 82801-3-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
