Lamin B2 Recombinant antibody, PBS Only
Lamin B2 Recombinant Antibody for IF/ICC, FC (Intra), Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IF/ICC, FC (Intra), Indirect ELISA
Conjugate
Unconjugated
CloneNo.
230184G4
Cat no : 82801-3-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
82801-3-PBS targets Lamin B2 in IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Lamin B2 fusion protein Ag1335 相同性解析による交差性が予測される生物種 |
Full Name | lamin B2 |
Calculated molecular weight | 68 kDa |
GenBank accession number | BC006551 |
Gene symbol | Lamin B2 |
Gene ID (NCBI) | 84823 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Lamins are nuclear membrane structural components that are important in structural integrity of the nucleus and may also interact with chromatin (PMID: 33033404). Research studies show that lamin B2 knockout mice exhibit neuronal developmental defects and that both proteins are essential for typical brain development (PMID: 20145110). Mutations in Lamin B2 can result in a susceptibility to developing acquired partial lipodystrophy, a rare disorder characterized by the progressive loss of subcutaneous fat in a bilaterally symmetrical fashion (PMID: 16826530).