Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
84771-4-PBS targets MAGI3 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | MAGI3 fusion protein Ag18394 相同性解析による交差性が予測される生物種 |
Full Name | membrane associated guanylate kinase, WW and PDZ domain containing 3 |
Calculated molecular weight | 1481 aa, 163 kDa |
Observed molecular weight | 140 kDa |
GenBank accession number | BC130409 |
Gene Symbol | MAGI3 |
Gene ID (NCBI) | 260425 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q5TCQ9 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
MAGI proteins are scaffolding proteins, belonging to the Membrane-Associated Guanylate Kinase Inverted proteins of the MAGUK family. There are three members of the MAGI subfamily, MAGI-1, MAGI-2, and MAGI-3. They are comprised of 6 PDZ domains, 2 WW domains, and 1 GUK domain. They have been proven to mediate the transport and signal transduction of various G protein-coupled receptors (GPCRs) (PMID: 29625175). The antibody is specific to MAGI3.