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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using MYO6 Recombinant antibody (84085-3-RR)

    WB analysis using 84085-3-RR (same clone as 84085-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84085-3-RR (MYO6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84085-3-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of LNCaP cells using MYO6 Recombinant antibody (84085-3-RR)

    WB analysis of LNCaP using 84085-3-RR (same clone as 84085-3-PBS)

    LNCaP cells were subjected to SDS PAGE followed by western blot with 84085-3-RR (MYO6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84085-3-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01001-1

    Cytometric bead array standard curve of MP01001-1

    Cytometric bead array standard curve of MP01001-1, MYO6 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84085-3-PBS. Detection antibody: 84085-1-PBS. Standard: Ag24906. Range: 0.781-100 ng/ml.

  • Cytometric bead array standard curve of MP01001-3

    Cytometric bead array standard curve of MP01001-3

    Cytometric bead array standard curve of MP01001-3, MYO6 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84085-2-PBS. Detection antibody: 84085-3-PBS. Standard: Ag24906. Range: 0.781-100 ng/ml.

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MYO6 Recombinant antibody, PBS Only (Capture/Detector)

MYO6 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 84085-3-PBS
Clone No.241251G11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Cytometric bead array, Indirect ELISA

Synonyms

Unconventional myosin 6, myosin VI, KIAA0389, DFNB37, DFNA22

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

84085-3-PBS targets MYO6 as part of a matched antibody pair:

MP01001-1: 84085-3-PBS capture and 84085-1-PBS detection (validated in Cytometric bead array)

MP01001-3: 84085-2-PBS capture and 84085-3-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen MYO6 fusion protein Ag24906 相同性解析による交差性が予測される生物種
Full Name myosin VI
Calculated molecular weight 1285 aa, 149 kDa
Observed molecular weight 145-150 kDa
GenBank accession numberBC146764
Gene Symbol MYO6
Gene ID (NCBI) 4646
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9UM54
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

MYO6, an actin-based motor protein, is the only myosin known to move toward the minus end of actin filaments. MYO6 is highly expressed in the inner and outer hair cells of the ear, retina, and polarized epithelial cells such as kidney proximal tubule cells and intestinal enterocytes. And it participates in a wide range of biological processes within cells, including clathrin-mediated endocytosis, vesicular membrane traffic, polarized secretion, and autophagy (PMID: 23620821; PMID: 28591580). Previous studies showed that MYO6 is upregulated in various types of cancer, and it has been widely reported to contribute to tumor cell migration and metastasis. Some articles indicate that MYO6 is associated with prostate cancer, lung cancer, human colorectal cancer and gastric cancer (PMID: 29022908).