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NLRC3 Polyclonal antibody, PBS Only

NLRC3 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 30455-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

30455-1-PBS targets NLRC3 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen NLRC3 fusion protein Ag32323 相同性解析による交差性が予測される生物種
Full Name NLR family, CARD domain containing 3
Calculated molecular weight 115 kDa
Observed molecular weight100-110 kDa
GenBank accession numberNM_178844
Gene Symbol NLRC3
Gene ID (NCBI) 197358
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ7RTR2
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells. In macrophages, NLRC3 inhibits the activation of the NF-κB signaling pathway, the STING/TBK1 signaling pathway, and the formation of the inflammasome. In the context of T cells immune response, NLRC3 prevents the activation of T cells by regulating the function of dendritic cells and directly influencing the function of T cells.

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