Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
80545-1-PBS targets Occludin in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with Human, Mouse, Pig samples.
Tested Reactivity | Human, Mouse, Pig |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Occludin fusion protein Ag26173 相同性解析による交差性が予測される生物種 |
Full Name | occludin |
Calculated molecular weight | 522 aa, 59 kDa |
Observed molecular weight | 59 kDa |
GenBank accession number | BC029886 |
Gene Symbol | Occludin |
Gene ID (NCBI) | 4950 |
RRID | AB_2918901 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q16625 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane domains, intracellular N and C termini and two extracellular loops. Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can exist in different isoforms, owing to modifications at the posttranscriptional and posttranslational levels, the monomeric occludin migrates as 53-65 kDa on SDS-PAGE (PMID: 22083955; 19457074).