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FcZero-rAb™ APC Anti-Human PD-L1/CD274 Rabbit Recombinant Antibody

PD-L1/CD274 FcZero-rAbTM Recombinant Antibody for FC
Cat No. APC-FcA98062
Clone No.240721H8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

CD274, PD-L1, PD L1, hPD-L1, B7-H1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  APC
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive FC detected inPHA treated human PBMCs

Recommended dilution

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

Product Information

APC-FcA98062 targets PD-L1/CD274 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein 相同性解析による交差性が予測される生物種
Full Name CD274 molecule
Calculated molecular weight 290 aa, 33 kDa
GenBank accession numberBC074984
Gene Symbol PD-L1
Gene ID (NCBI) 29126
Conjugate APC Fluorescent Dye
Excitation/Emission maxima wavelengths650 nm / 660 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.09% sodium azide and 0.5% BSA.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Programmed cell death ligand 1 (PD-L1, CD274, or B7-H1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. PD-L1 is suggested as a negative regulator of T and B cell, and plays important role in mediating tolerance of lymphocytes to self-antigens. It is also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PD-1-independent manner.

Protocols

Product Specific Protocols
FC protocol for APC PD-L1/CD274 antibody APC-FcA98062Download protocol
Standard Protocols
Click here to view our Standard Protocols
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